WebMaraviroc is a CYP3A4/P-glycoprotein (P-gp) substrate and amiodarone is a CYP3A4/P-gp inhibitor. Monitor for an increase in adverse effects with concomitant use. Amlodipine: (Minor) Use caution if coadministration of maraviroc with amlodipine is necessary, due to a possible increase in maraviroc exposure.
Selzentry (maraviroc) dose, indications, adverse effects ... - PDR
WebMaraviroc is the first approved CCR5 antagonist (Fig. 130-6 ). HIV entry requires viral gp120 to sequentially bind CD4 and a surface co-receptor, either CCR5 or CXCR4. Maraviroc is an allosteric inhibitor of the gp120-CCR5 interaction that blocks HIV attachment to target cells and thereby reduces viral replication. WebOct 12, 2024 · Maraviroc is an antiviral medicine that prevents human immunodeficiency virus from multiplying in your body.. Maraviroc is used with other medications to treat CCR5-tropic HIV type 1, a virus that can cause acquired immunodeficiency syndrome (). Maraviroc is not a cure for HIV or AIDS.. Maraviroc is for use in adults and children who … the olivine apartments austin tx
Selzentry (maraviroc): Basics, Side Effects & Reviews - GoodRx
WebSelzentry (Maraviroc) Dosage Form (Strength) Oral solution (20 mg/mL) Tablet (25 mg and 75 mg) Indication . Treatment of HIV-1 . Review Team . Jenny Zheng, Justin Earp, Su-Young Choi . WebJun 22, 2024 · This is a bicentric, phase 2, randomized, open-label study to evaluate the efficacy and safety of maraviroc associated with standard treatment in hospitalized patients with pulmonary SARS-CoV-2 infection (COVID-19), to prevent disease progression to severe Acute Respiratory Distress Syndrome (ARDS). WebMaraviroc is indicated, in combination with other antiretroviral medications, for the treatment of only CCR5-tropic HIV-1 infection. [1] [2] Side effects [ edit] Maraviroc can cause serious, life-threatening side effects. These include liver problems, skin reactions, and allergic reactions. mickey\u0027s burgers everett