WebIRF4. Interferon regulatory factor 4 (IRF4) also known as MUM1 is a protein that in humans is encoded by the IRF4 gene, [5] [6] [7] located at 6p25-p23. IRF4 functions as a key regulatory transcription factor in the development of human immune cells. [8] [9] The expression of IRF4 is essential for the differentiation of T lymphocytes and B ... WebSSI Data The SSI data file below shows the latest available IRF-specific data to compute an IRF's SSI ratio for the specified fiscal year (FY). An IRF may use this ratio as part of the …

Immature reticulocyte fraction detects erythropoiesis

WebApr 17, 2015 · The NF-κB and IRF transcription factor families are major players in inflammation and antiviral response and act as two major effectors of the innate immune response (IIR). The regulatory mechanisms of activation of these two pathways and their interactions during the IIR are only partially known. Results WebApr 4, 2024 · Interferon regulatory factor 1 (IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC). Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN. HDAC1 potentiates CD4 + T cell activation by inhibiting miR-124 and promoting IRF1 in systemic lupus erythematosus. cricket roof chimney

IRF1 - an overview ScienceDirect Topics

WebHuman immunodeficiency virus type 1 (HIV-1) gene expression is controlled by a complex interplay between viral and host factors. We have previously shown that interferon-regulatory factor 1 (IRF-1) is stimulated early after HIV-1 infection and regulates promoter transcriptional activity even in the absence of the viral transactivator Tat. WebJan 21, 2024 · Abstract The eponymous member of the interferon regulatory factor (IRF) family, IRF1, was originally identified as a nuclear factor that binds and activates the promoters of type I interferon genes. Webinterferon regulatory factor 5 Normal Function The protein produced from the IRF5 gene, called interferon regulatory factor 5 (IRF5), acts as a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity of certain genes. cricketroomate bedroom prank